Phosphodiesterase, Phosphatase, Kinase, and ELISA Assay Development

Altogen Labs offers kinase, phosphatase, and phosphodiesterase assay development services for screening and validation studies. For each project, an individual pathway is defined that matches the biology and chemistry requirements of the target to the most appropriate assay technology platform available. Company scientists have experience developing assays with all major fluorometric readouts and biologically relevant formats, in addition to high-content applications: fluorescence, time-resolved fluorescence resonance energy transfer, luminescence, absorbance, calcium mobilization (FLIPR), ELISA, cellular imaging, fluorescent microscopy, enzyme assays, reporter assays, viability assays, and protein translocation. Compound profiling is supported by qRT-PCR, Western blot, FACS and other expression and functional assays.

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